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Surveillance of pesticide poisoning in Colombia


The objective of this article is to realize a critical review of the epidemiologic surveillance of pesticide-related health effects in Colombia. First, it describes  the historic changes in the exposure to pesticides in the country, the expected and potential adverse health effects (chronic, acute, and sub-acute). Second, it reviews some epidemiologic surveillance systems actually used in Colombia with their strongholds and weakness. Finally, it proposes some basic issues to improve this important public health activity.

Key words: Pesticide, epidemiologic surveillance, Colombia, public health




Biological indicators for the assessment of human exposure to organophosphorous compounds.


Autor: Podolak M, Panasiuk L.

Título en español: Indicadores biológicos para la evaluación de la exposidión humana a compuestos órganofosforados.

Publicación: Przegl Lek. 1997;54(10):719-22.
Tipo documento: Publication Types: • Clinical Trial• Controlled Clinical Trial
Abstract: The aim of the present study is to review selected biological effects of organophosphorous compounds used as pesticides and to discuss their significance in terms of occupational exposure. The results of a long-term study of the red cells and plasma ChE in group of workers engaged in the production of pesticides are also presented. Cholinesterase activity in plasma and red blood cells was determined spectrophotometrically by the Ellman modified method. Occupational exposure to pesticides was analysed by the Durham and Wolf method. Conclusions: 1. Cholinesterase activity in blood serum of the workers employed at the production of organophosphorous compounds is statistically significantly lower, compared to the control group and the lower accepted standard limit. 2. Cholinesterase activity in plasma seems to be a more sensitive indicator of exposure, compared to the activity of enzyme contained in erythrocytes after a long-lasting exposure to low levels of organophosphorous compounds. 3. Changes in cholinesterase activity according to the level of exposure show a better correlation if the exposure is expressed in % of the toxic dose/day than in mg/day. Toxicological properties of organophosphorous compounds are of the great importance for this correlation.
PMID: 9478093 [PubMed – indexed in MEDLINE]

Título: Organophosphate pesticide exposure and neurobehavioral performance in agricultural and non-agricultural Hispanic workers.


Autor:Rothlein J, Rohlman D, Lasarev M, Phillips J, Muniz J, McCauley L.

Publicación: Environ Health Perspect. 2006 May;114(5):691-6. Center for Research on Occupational and Environmental Toxicology, Oregon Health and Science University, Portland, Oregon, USA.


Publication Types: Comparative Study Research Support, N.I.H., Extramural
Abstract: Our understanding of the health risks of farmworkers exposed to pesticides in their work and home environments is rapidly increasing, although studies designed to examine the possible neurobehavioral effects of low-level chronic pesticide exposure are limited. We measured dialkyl phosphate urinary metabolite levels, collected environmental dust samples from a subset of homes, obtained information on work practices, and conducted neurobehavioral tests on a sample of farmworkers in Oregon. Significant correlations between urinary methyl metabolite levels and total methyl organophosphate (azinphos-methyl, phosmet, malathion) house dust levels were observed. We found the neurobehavioral performance of Hispanic immigrant farmworkers to be lower than that observed in a nonagricultural Hispanic immigrant population, and within the sample of agricultural workers there was a positive correlation between urinary organophosphate metabolite levels and poorer performance on some neurobehavioral tests. These findings add to an increasing body of evidence of the association between low levels of pesticide exposure and deficits in neurobehavioral performance.

PMID: 16675422 [PubMed – index


Título: Nombre del artículo Human exposure to pesticidas
Autor (es) Maroni, Marco
Nombre del artículo en español Exposición humana a pesticidas


Publicación (nombre, volumen, nº, fecha, página) International Centre for Pesticides Safety

Tipo de publicación (periódica, libro, fecha, páginas): conferencias curso

Tipo de documento (artículo, investigación original, revisión sistemática, metanálisis, protocolo, guía, norma, legal) no aplica

Para artículos de investigación original:

tipo de investigación o diseño: no aplica

País Chile

Fuente de origen (base indexada, literatura gris): literatura gris

Palabras clave:: no aplica

Abstract original (transcripción): Curso en que el Dr Maroni se refiere a la exposición ocupacional y ambiental considerando las tareas de producción, formulación, aplicación y de trabajo agrícola directo. Tambíén hace referencia a la exposición del trabajador industrial. Menciona las bases de datos genéricas sobre exposición como PHED de USA, BBA de Alemania, POEM predictive operator exposure model de Gran Bretaña, EUROPOEM de Europa que muestran la exposición en distintos escenarios geográficos. Respecto del rol del monitoreo biológico se refiere a las condiciones de salud previa, el uso de EPP y los distintos tipos de trabajo. Se especifica la definición de “caso” para la vigilancia de las exposiciones agudas, los criterios de diagnóstico por laboratorio de manera que se pueda utilizar la matriz que incluya los tres elementos que permitan documentar la exposición, los efectos en la salud y la relación causal. Para el grupo de órganofosforados, describe los efectos agudos, los factores que potencian la toxicidad, los primeros auxilios, los efectos retardados y la vigilancia médica considerando el monitoreo biológico y las contraindicaciones para exponerse.

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